Introduction
In recent years, hyaluronic acid fillers have gained immense popularity in the field of cosmetic dermatology. These fillers offer a non - invasive way to rejuvenate and enhance facial features, with benefits such as easy access, minimal downtime, and consistent rejuvenation results. However, not all filler treatments yield satisfactory outcomes. Poor injection techniques by inexperienced injectors, or simply a change in the patient's aesthetic preferences, can lead to dissatisfaction with the final results. This is where hyaluronidase comes into play. Hyaluronidase is an injectable enzyme that can reverse the effects of hyaluronic acid fillers, restoring the skin to its pre - injection state. In New York City, there are several authorized hospitals and clinics that offer hyaluronidase dissolution services. In this article, we will not only explore the top 3 authorized hospitals but also provide comprehensive information about hyaluronidase, its uses, effects, and more.
What is Hyaluronidase?
Definition and Sources
Hyaluronidase is an enzyme that occurs naturally in the body. It is produced by white blood cells to facilitate their movement through connective tissues. It has also been discovered in insects, mammalian tissues, and even snake venom. There are different classifications of hyaluronidase, with the most common being Hyal1 and Hyal2. Hyal2 has less enzyme activity but can break down hyaluronic acid with a higher molecular weight.
For medical use, hyaluronidase is typically isolated and purified. Injectable hyaluronidase comes in several FDA - approved brand - name formulations, including Hydase, Hylenex, Amphadase, and Vitrase. These formulations usually contain the enzyme collected from purified bovine tissue (ovine testicular hyaluronidase) or derived from human albumin sources (recombinant human hyaluronidase). Brands like Hylenex, which uses hyaluronidase derived from human albumin sources, minimize the risk of an allergic reaction.
Functions in the Body and Medical Applications
Hyaluronidase has a variety of FDA - approved medical functions. It can improve the diffusion of anesthetics in pain therapy, aid in the absorption of treatment agents in chemotherapeutics and ophthalmic surgery, act as a spreading agent in subcutaneous injections, and is also used off - label to dissolve hyaluronic acid fillers.
It works by breaking down the glycosidic linkages of hyaluronic acid through a hydrolysis process. This leads to a decrease in the viscosity or thickness of hyaluronic acid molecules, contributing to the removal of hyaluronic acid in the treatment area. For example, when injected into areas with unwanted hyaluronic acid fillers, it can reverse the cosmetic effects of the fillers.
How Hyaluronidase Works for Filler Dissolution
The Mechanism of Action
Hyaluronidase breaks down the linkages between hyaluronic acid molecules in dermal fillers. When injected subcutaneously, it decreases the amount of hyaluronic acid from the filler, ultimately reversing its cosmetic effects. However, patients should wait at least two weeks after their dermal filler injections to consider hyaluronidase, as the fillers can take up to two weeks to settle.
The Treatment Process
The process of getting hyaluronidase injections is relatively simple. First, patients meet with a medical professional, such as a board - certified dermatologist. The doctor will discuss the patient's concerns with the current hyaluronic acid filler results, their medical history, and develop a treatment plan. The doctor will ask about the amount and type of hyaluronic acid fillers to be dissolved.
During the injection procedure, the doctor administers hyaluronidase to the initial hyaluronic acid filler treatment area. After the treatment, patients can resume normal activity as there is no significant downtime. Some potential side effects include swelling, bruising, and tenderness at or near injection sites, which usually resolve independently within one to two weeks. The effects of hyaluronidase are usually apparent after just 48 hours, and for most patients, the appearance of the previous dermal filler will be completely reversed after one treatment. However, some patients may need a second or third treatment.
Benefits and Risks of Hyaluronidase Treatment
Benefits
- Reversing Unwanted Filler Results: It is the gold standard treatment for dissolving unwanted or misplaced hyaluronic acid fillers that have produced poor cosmetic results. Patients can return to their pre - filler appearance.
- Quick Results: The effects of hyaluronidase usually start to appear within 2 - 3 days, and most patients see complete results within two weeks.
- Minimal Downtime: Patients can resume their normal activities right after the treatment.
- Customizable Treatment: A skilled doctor can tailor the treatment plan according to the patient's specific needs.
Risks and Side Effects
Side effects of hyaluronidase are generally rare. The most common ones include mild swelling, bruising, and tenderness at or near injection sites, which resolve within one week. There is also a small risk of a mild allergic reaction, with a reported incidence between 0.05% and 0.69%. A skin test may be performed before the injections to evaluate for hypersensitivity. Repeated injections of relatively large amounts may lead to the production of neutralizing antibodies, reducing the effectiveness of hyaluronidase in dissolving fillers. Additionally, hyaluronidase should not be injected via intravenous injections, as it can put patients at risk for allergic reactions and more adverse events.
Top 3 Authorized Hospitals for Hyaluronidase Dissolution in New York City
1. Michele Green MD
Dr. Michele Green is an internationally renowned board - certified dermatologist with over two and a half decades of experience. She takes a holistic approach to facial rejuvenation, embracing a “less - is - more” philosophy. Her dedication to her patients and expertise have led her to be consistently identified as one of New York City's best dermatologists by Castle Connolly, New York Magazine, and Super Doctors.
Dr. Green uses Hylenex, a synthetic, recombinant DNA product made from human products, for hyaluronidase treatments. Recombinant human hyaluronidase has a purity 100 times higher than some of the bovine preparations, and allergic reactions to Hylenex are very rare. She customizes each patient's treatment plan to suit their particular skin concerns and overall aesthetic goals.
2. Skinly Aesthetics
At Skinly Aesthetics, Dr. Schwarzburg offers unparalleled skill and experience with Hylenex. He is a renowned board - certified cosmetic dermatologist and wellness expert with over a decade of experience and has performed tens of thousands of procedures.
Dr. Schwarzburg ensures that patients are guided through the process of filler dissolution with precision and care. He selects Hylenex for his patients due to its consistency and safety. The clinic is situated in a prime upper - east - side location in New York City and specializes in personalized skincare, body contouring, and wellness treatments.
3. MiracleFace MedSpa
MiracleFace MedSpa is another authorized place for hyaluronidase dissolution. Their professionals are dedicated to helping patients dissolve unwanted fillers and regain their confidence. The doctors at MiracleFace have the licenses and qualifications to perform the procedure in a highly professional manner.
The clinic uses hyaluronidase to dissolve common hyaluronic acid - based fillers like Juvederm and Restylane. The hyaluronidase injection is a quick procedure, often referred to as a “lunchtime procedure,” taking about 30 minutes. In most cases, just one session is enough to get the desired results, and patients can resume their daily activities immediately as there is no downtime.
Cost of Hyaluronidase Treatment
The cost of hyaluronidase treatment varies depending on several factors, such as the amount of filler needed to be dissolved, the type of filler, the treatment area, and the provider's expertise. On average, the treatment cost is around $1,000. However, it can range from $400 - $1500. When you have a consultation with a doctor, they will be able to give you a more accurate quote based on your specific situation.
Frequently Asked Questions about Hyaluronidase
What is hyaluronidase injection used for?
Hyaluronidase injections are most commonly used to dissolve hyaluronic acid dermal fillers. They are also used to improve the dispersion of drugs injected into the skin, as an adjunct in subcutaneous urography for improved resorption of radiopaque agents, and in other medical applications such as edema reduction (off - label use), treatment of vitreous hemorrhage, and preventing tissue necrosis in chemotherapy patients with extravasation.
How long does it take for hyaluronidase to dissolve filler fully?
Many patients start to see the treatment's effects 2 - 3 days after the procedure, with full effects being visible around two weeks post - treatment. However, results can vary due to the different degrees of density of hyaluronic acid fillers. Some fillers may require an increased amount or repeated number of treatments to dissolve them completely.
How long after hyaluronidase can I get dermal fillers?
Patients should wait at least two weeks after their last hyaluronidase injections before having dermal fillers. This allows any side effects of the hyaluronidase injections, such as swelling, bruising, or tenderness at or near injection sites, to resolve. If dermal fillers are injected too soon, there is a potential risk of the hyaluronidase dissolving the new fillers.
How to dissolve filler without hyaluronidase?
Hyaluronidase is the only effective and safe treatment method for dissolving hyaluronic acid dermal fillers. For dermal fillers that are not composed of hyaluronic acid, such as Radiesse (calcium hydroxylapatite) and Sculptra (poly - l - lactic acid), patients must wait for the effects of these dermal fillers to wear off over time.
Does hyaluronidase dissolve Botox?
No, Botox is a neurotoxin, not a hyaluronic acid dermal filler. Only hyaluronic acid fillers can be dissolved with hyaluronidase. Botox inhibits nerve signals to certain facial muscles related to expression, and its effects typically last up to four months.
Conclusion
Hyaluronidase offers a reliable solution for those who are unhappy with the results of their hyaluronic acid filler treatments. It is a safe and effective enzyme that can reverse the cosmetic effects of fillers, restoring the skin to its natural state. In New York City, there are top - notch authorized hospitals and clinics like Michele Green MD, Skinly Aesthetics, and MiracleFace MedSpa that provide high - quality hyaluronidase dissolution services.
If you have had a less - than - satisfactory filler experience, don't hesitate to explore hyaluronidase treatment. However, it is crucial to consult with a qualified and experienced medical professional to ensure the best results and minimize potential risks. Take the first step towards achieving your desired aesthetic by scheduling a consultation with one of these top authorized providers in New York City today!
