The field of cosmetic dermatology is constantly evolving, with new procedures and treatments emerging to address various concerns. One such innovation is the use of hyaluronidase, a powerful enzyme that can dissolve hyaluronic acid-based fillers like Juvederm Vycross. In this comprehensive guide, we will delve into the mysteries of hyaluronidase and explore its various aspects, ranging from its mechanism of action to its applications and potential side effects.
Understanding Hyaluronidase: How Does It Work?
Hyaluronidase is an enzyme that breaks down hyaluronic acid, a naturally occurring substance in the body responsible for maintaining moisture and elasticity in the skin. When injected into the targeted area, hyaluronidase works by breaking the molecular bonds of hyaluronic acid, leading to its degradation and eventual elimination. This enzymatic action allows for the quick reversal of hyaluronic acid-based fillers, making it an invaluable tool for correcting overfilled or improperly placed injections.
Applications of Hyaluronidase: Versatility at Its Best
Hyaluronidase can be used in a variety of scenarios, proving its versatility and efficacy. The most common application is the correction of hyaluronic acid-based filler complications, such as overfilled lips or under-eye hollows. By injecting hyaluronidase into the affected area, the excess filler can be rapidly dissolved, restoring a more natural and balanced appearance.
In addition to its corrective applications, hyaluronidase can also be utilized during non-surgical rhinoplasty procedures, commonly known as liquid nose jobs. By strategically injecting small amounts of hyaluronidase, the shape and contour of the nose can be subtly altered, providing a non-permanent alternative to surgical rhinoplasty.
Hyaluronidase has also shown promise in managing complications resulting from vascular occlusion, a rare but serious side effect of filler injections. By rapidly breaking down the injected hyaluronic acid, hyaluronidase can help restore blood flow and prevent potential tissue necrosis.
The Procedure: What to Expect
The procedure involving hyaluronidase is relatively straightforward. The targeted area is first cleansed and prepared, followed by the injection of the enzyme using a fine needle. Results can be seen almost immediately, as the hyaluronic acid filler begins to break down. Depending on the extent of correction needed, multiple sessions may be required to achieve the desired outcome.
It is important to note that the use of hyaluronidase should only be performed by experienced and qualified practitioners, as the enzyme must be administered in precise amounts and locations to avoid any unwanted complications.
Potential Side Effects and Considerations
As with any medical procedure, there are potential side effects and considerations to be aware of when using hyaluronidase. While rare, allergic reactions can occur, and it is crucial to disclose any known allergies to the practitioner prior to treatment.
Some individuals may experience temporary swelling, redness, or bruising at the injection site. These effects typically subside within a few days. It is important to follow post-treatment care instructions provided by the practitioner to ensure optimal healing.
Pricing: What Can You Expect?
The cost of hyaluronidase treatments can vary depending on various factors, including the location, practitioner's experience, and the amount of product needed for correction. On average, the price of a single hyaluronidase session can range from $300 to $800.
FAQs
Q: How long does it take for hyaluronidase to dissolve filler?
A: The speed of hyaluronidase's action can vary depending on the individual and the type of filler used. In most cases, partial or complete dissolution can occur within a few hours or days.
Q: Is hyaluronidase permanent?
A: No, hyaluronidase is not a permanent treatment. Its effects are temporary, and the body will metabolize the enzyme over time.
Q: How soon can I get re-injected with filler after hyaluronidase treatment?
A: It is best to wait for at least 48 hours before considering re-injection with filler after hyaluronidase treatment. This allows the area to stabilize and ensures accurate assessment of the correction needed.
Q: Are there any long-term risks associated with hyaluronidase?
A: Long-term risks with hyaluronidase are minimal. However, it is important to undergo the procedure with an experienced practitioner to minimize the chances of complications.
References
1. American Society for Dermatologic Surgery. (2017). Hyaluronic Acid Fillers & Hyaluronidase: What You Should Know. Retrieved from
2. Cohen, J. L., Dayan, S. H., Brandt, F., & Manolidis, S. (2012). Treatment of hyaluronic acid filler-induced impending necrosis with hyaluronidase: consensus recommendations. Aesthetic Surgery Journal, 32(3), 330-342.
3. Monheit, G. D. (2010). Safety of nonanimal stabilized hyaluronic acid dermal fillers in patients with depression or bipolar disorder: a retrospective chart review. Journal of Drugs in Dermatology, 9(3), 215-218.
4. Palm, M. D., & Goldman, M. P. (2015). Hyaluronidase caveats. Dermatologic Surgery, 41(Supplement 1), S347-S353.
5. Tadisina, K. K., & Chopra, K. (2019). Technique and Safety of Hyaluronidase in the Treatment of Hyaluronic Acid Filler Blindness. JAMA facial plastic surgery, 21(5), 396-397.
